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1 OMIM reference -
1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 3
2 OMIM references -
4 associated genes
6 signs/symptoms
Coronary artery disease - hyperlipidemia - hypertension - diabetes - osteoporosis
Idiopathic juvenile osteoporosis

LRP6 DKK1
LRP5
WNT1
WNT3A


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
LRP6
LRP6
LRP6
(0.89)
(0.85)
(0.84)
DKK1
WNT1
WNT3A



Citations in the biomedical literature:


Coronary artery disease - hyperlipidemia - hypertension - diabetes - osteoporosis
LRP6
Idiopathic juvenile osteoporosis
DKK1 LRP5 WNT1 WNT3A



Coronary artery disease - hyperlipidemia - hypertension - diabetes - osteoporosis
Idiopathic juvenile osteoporosis

Synonym(s):
(no synonyms)

Synonym(s):
- IJO
- Juvenile osteoporosis

Classification (Orphanet):
- Rare cardiac disease
- Rare genetic disease
Classification (Orphanet):
- Rare bone disease
- Rare developmental defect during embryogenesis
- Rare genetic disease

Classification (ICD10):
(no data available)
Classification (ICD10):
- Diseases of the musculoskeletal system and connective tissue -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: no data available
Average age of death: -
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: unknown
Average age onset: childhood
Average age of death: -
Type of inheritance: autosomal dominant

External references:
1 OMIM reference -
No MeSH references
External references:
2 OMIM references -
No MeSH references

Idiopathic juvenile osteoporosis

Very frequent
- Bone pain
- Mutiple fractures / bone fragility
- Osteoporosis / osteopenia / demineralisation / osteomalacia / rickets

Frequent
- Abnormal gait
- Motor deficit / trouble

Occasional
- Kyphosis


Coronary artery disease - hyperlipidemia - hypertension - diabetes - osteoporosis

(no data available)